Improved quantitative method for G6PD deficiency detection
نویسندگان
چکیده
منابع مشابه
G6PD deficiency.
T HIRTY-FIVE YEARS ago Dr William Dameshek, the first editor of the emerging journal Blood, invited me to write a review on “The Hemolytic Effect of Primaquine.”’ At the time, primaquine sensitivity, which had just recently been shown to be caused by a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD); represented a unique example of an inherited deficiency of an enzyme that cau...
متن کاملScreening for G6pd Deficiency in Blood Donors
Original Article AIMS AND OBJECTIVES:1. To screen blood donors [n=100] for G6PD deficiency, particularly in males. 2. To determine the frequency of G6PD deficiency in the population tested. MATERIALS AND METHODS: 50 samples of donors' blood from at KIMS Blood Bank. Method of collection of data: The Methaemoglobin reduction test: Principle: Sodium Nitrate oxidises MethHb to Hb and the subsequent...
متن کاملEvaluation of G6PD Deficiency in Acne Patients
Introduction: Various factors are involved in the pathogenesis of acne vulgaris. Recently, G6PD deficiency has been proposed in the pathogenesis of acne. G6PD has an important role in the oxidant/antioxidant balance. According to this theory, antioxidants are used in the treatment of acne recently. The aim of this study was to evaluate G6PD deficiency in patient with acne vulgaris. Methods: The...
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15 صفحه اولModelling primaquine-induced haemolysis in G6PD deficiency
Primaquine is the only drug available to prevent relapse in vivax malaria. The main adverse effect of primaquine is erythrocyte age and dose-dependent acute haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd). As testing for G6PDd is often unavailable, this limits the use of primaquine for radical cure. A compartmental model of the dynamics of red blood c...
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ژورنال
عنوان ژورنال: Journal of Clinical Laboratory Analysis
سال: 2007
ISSN: 0887-8013,1098-2825
DOI: 10.1002/jcla.20117